Antilymphocyte serum and tissue culture used to investigate role of cell-mediated response in viral encephalitis in mice.

نویسندگان

  • G A Rook
  • H E Webb
چکیده

Antilymphocyte serum given to suppress selectively the cell response to Langat virus in Swiss albino mice prolonged the average survival times. In vitro, lymph-node cells from virus-immunized mice were strongly cytotoxic for syngenic non-neuronal brain cells infected with virus. The implications of these findings are discussed, with particular reference to the concept of autoimmunity.

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عنوان ژورنال:
  • British medical journal

دوره 4 5729  شماره 

صفحات  -

تاریخ انتشار 1970